The San Francisco 49ers host the Los Angeles Rams on Thursday at 8:15 p.m. ET, in a battle between a pair of the best offensive performers in the NFL in George Kittle and Kyren Williams.
From an offensive angle, the Rams are posting 340.7 total yards per contest (15th-ranked). They rank 27th in the NFL on the other side of the ball (366.1 total yards allowed per game). The 49ers have been clicking on all fronts this season, as they rank fourth-best in total offense (378.5 yards per game) and third-best in total defense (298.5 yards allowed per game).
Rams vs 49ers: live streaming info, TV channel & game time
Rams vs 49ers betting lines
NFL odds courtesy of BetMGM. Odds updated Thursday at 4:33 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread Favorite: 49ers (-3)
Moneyline: 49ers (-152), Rams (+128)
Total: 49 points
Watch 49ers vs. Rams on Fubo!
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