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The San Francisco 49ers and Miami Dolphins play Sunday, Dec. 22, at Miami’s Hard Rock Stadium in a game on the NFL Week 16 schedule.
Which team will win the NFL Week 16 game?
Check out these NFL Week 16 picks and NFL Week 16 predictions for the game, which can be seen at 2:25 p.m. MST on CBS (stream with FUBO).
The Dolphins are a 1.5-point favorite over the 49ers in NFL Week 16 odds for the game, courtesy of BetMGM Sportsbook.
Miami is -125 on the moneyline, while San Francisco is +105.
The over/under (point total) is set at 46 points.
NFL Week 16 picks: Broncos vs Chargers | Texans vs Chiefs | Steelers vs Ravens | Giants vs Falcons | Patriots vs Bills | Cardinals vs Panthers | Lions vs Bears | Titans vs Colts | Rams vs Jets | Eagles vs Commanders | Browns vs Bengals | Vikings vs Seahawks | Jaguars vs Raiders | 49ers vs Dolphins | Bucs vs Cowboys | Saints vs Packers | The Arizona Republic’s predictions
Watch 49ers at Dolphins with FUBO (free trial)
Jeremy Cluff writes: “Both of these teams had high expectations this season and have failed to meet those expectations. The 49ers, however, are just a mess.”
Bookies.com: Bet the over in 49ers vs Dolphins game
Bill Speros writes: “The 49ers are the latest victim of the NFL’s merciless ‘We Lost The Super Bowl Hangover.’ San Francisco is likely out of the postseason. The Dolphins hit some choppy waters in their 20-12 loss at Houston Sunday. Miami needs a win here at home to stay playoff viable. The 49ers are coming off the mini-bye. They’re still alive in the NFC West, but we’re not sure even Robert Oppenheimer could figure out the math there. Tua and the Dolphins finally drop the Big One at home. Each of their past 5 games at home have gone over on the points total.”
The site’s formula predicts that the 49ers will win the NFL Week 16 game against the Dolphins.
ESPN: 49ers have a 55% chance to beat Dolphins on Sunday
The site gives the Dolphins a 44.6% shot at winning the NFL Week 16 game, with the remaining percentage accounting for a tie.
Dimers: Dolphins 24, 49ers 24
That’s right. The site predicts a tie in this game on Sunday. It writes: “After extensive simulations, our model gives the 49ers a win probability of 52%, while the Dolphins have a win probability of 48%.”
Sportsnaut: Dolphins 24, 49ers 21
Matt Johnson writes: “Both teams are banged up heading into Week 16, with uncertainty at both tackle spots on the Miami Dolphins offensive line while the San Francisco 49ers deal with absences on both sides of the ball. Miami’s run defense – 83.3 rush ypg in last eight games – is still holding up well, which could be enough in a low-scoring game.”
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Reach Jeremy Cluff at [email protected]. Follow him on X, formerly Twitter @Jeremy_Cluff.
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