At Levi’s Stadium on Monday, Jahmyr Gibbs and the Detroit Lions face George Kittle and the San Francisco 49ers in a matchup featuring a pair of the biggest stars in the league offensively, starting at 8:15 p.m. ET.
The 49ers rank eighth in the NFL with 365.7 total yards per game, but they’ve been led by their defense, which ranks second-best by surrendering only 304.3 total yards per game. Offensively, the Lions have been a top-five unit, ranking best in the NFL by compiling 32.9 points per game. They rank seventh on defense (19.9 points allowed per game).
49ers vs Lions: live streaming info, TV channel & game time
49ers vs Lions betting lines
NFL odds courtesy of BetMGM. Odds updated Monday at 12:45 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread Favorite: Lions (-3.5)
Moneyline: Lions (-188), 49ers (+156)
Total: 50.5 points
Watch Lions vs. 49ers on Fubo!
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