The San Francisco Giants (2-1) and Houston Astros (2-1) open a 3-game series Monday. First pitch from Daikin Park is scheduled for 8:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the Giants vs. Astros odds and make our expert MLB picks and predictions for the best bets.
Season series: First meeting; Giants won 2-1 last season
San Francisco improved to 2-1 on the season with a 6-3 victory over the Cincinnati Reds Sunday as a -122 road favorite. LHP Robbie Ray earned his first win, allowing 3 runs over 5 1/3 innings. 3B Matt Chapman and LF Heliot Ramos each homered and drove in 2 runs to lead the offense.
Houston has also won 2 of its first 3 games after beating the New York Mets 2-1 Saturday as a -115 home favorite. RHP Spencer Arrighetti earned his first victory, allowing just 1 hit and 1 run over 6 strong innings. SS Jeremy Peña provided the offense with a solo homer.
Giants at Astros projected starters
RHP Jordan Hicks vs. RHP Ronel Blanco
Hicks (4-7, 4.10 ERA in 2024) made 20 starts and 9 relief appearances last year. He had a 1.45 WHIP, 3.9 BB/9 and 7.9 K/9 through 109 2/3 innings.
2024 road stats: 2-4, 4.14 ERA (50 IP, 23 ER), 1.70 WHIP, 9.7 K/9 in 10 starts and 4 relief appearances
2024 vs. Astros: 0-1, 1 home start (June 11), 4 2/3 IP, 3 ER, 5 H, 1 BB, 5 K in 3-1 loss
Career vs. Astros: 0-1, 4.76 ERA (5 2/3 IP, 3 ER), 1.06 WHIP, 9.5 K/9 in 1 start and 1 relief appearance
Blanco (13-6, 2.80 ERA in 2024) made 29 starts and 1 relief apperance last season. He had a 1.09 WHIP, 3.7 BB/9 and 8.9 K/9 through 167 1/3 innings.
2024 home stats: 6-4, 3.19 ERA (87 1/3 IP, 31 ER), 1.10 WHIP, 9.6 K/9 in 15 starts and 1 relief appearance
2024 vs. Giants: 1-0, 1 road start (June 11), 6 IP, 1 ER, 3 H, 1 BB, 8 K
Career vs. Giants: 1-0, 1.29 ERA (7 IP, 1 ER), 1.00 WHIP, 10.3 K/9 in 1 start and 1 relief appearance
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Giants at Astros odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated at 12:42 p.m. ET.
Moneyline (ML): Giants +105 (bet $100 to win $105) | Astros -125 (bet $125 to win $100)
Run line (RL)/Against the spread (ATS): Giants +1.5 (-225) | Astros -1.5 (+170)
Over/Under (O/U): 8 (O: +100 | U: -120)
Giants at Astros picks and predictions
Prediction
Astros 4, Giants 3
Moneyline
BET ASTROS (-125).
With Blanco on the mound — coming off the best season of his career — the Astros hold a clear advantage. They’ve won 2 of their first 3 games at home and will face Hicks, who struggled on the road last season with an ERA over 4.00.
Run line/Against the spread
PASS.
With both teams off to strong starts, the moneyline offers the best value.
Over/Under
BET UNDER 8 (+100).
The Astros have hit the Under in 9 of their last 10 games dating back to last season, including all 3 games this year. They’ve struggled offensively, scoring 3 or fewer runs in each contest while allowing just 5 total runs.
The Giants have allowed 3 runs in consecutive games.
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