Fernando Tatis Jr. and the San Diego Padres match up with Willy Adames and the San Francisco Giants on Wednesday at 4:10 p.m. ET at PETCO Park.
The 9.2 strikeouts per nine innings put together by the Giants pitching staff ranks sixth in MLB. The Padres have the second-best ERA (2.86) in the majors this season.
Get ready for the Giants vs. Padres with what you need to know about Wednesday’s game, including viewing options.
Giants vs. Padres: live stream info, TV channel & game time
Game day: Wednesday, April 30, 2025Game time: 4:10 p.m. ETLocation: San Diego, CaliforniaStadium: PETCO ParkTV channel: San Diego Padres (NEW)Live stream: Watch LIVE with Fubo! (Regional restrictions may apply)
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Giants vs. Padres odds & betting lines
Favorite: Giants (-123, bet $123 to win $100)Underdog: Padres (+104, bet $100 to win $104)Over/under: 7
MLB odds courtesy of BetMGM Sportsbook. Odds updated Wednesday at 3:09 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
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