The NFL released its full 2025 regular-season schedule. We know the Arizona Cardinals’ schedule.
What we don’t readily know are their opponents’ schedules. In particular, it is good to know the teams their opponents play before and after their game against the Cardinals.
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Since the Cardinals play two games each against their NFC West opponents, let’s have a look at their schedules and the teams they play the week prior and the week after.
Here is the schedule for the San Francisco 49ers.
San Francisco 49ers 2025 regular-season schedule
Week 1, Sept. 7: 49ers at Seattle Seahawks (1:05pm, FOX)
Week 2, Sept. 14: 49ers at New Orleans Saints (10:00am, FOX)
Week 3, Sept. 21: 49ers vs. Arizona Cardinals (1:25pm, FOX)
Week 4, Sept. 28: 49ers vs. Jacksonville Jaguars (1:05pm, FOX)
Week 5, Oct. 2: 49ers at Los Angeles Rams (5:15pm, Prime Video) [TNF]
Week 6, Oct. 12: 49ers at Tampa Bay Buccaneers (10:00am, CBS)
Week 7, Oct. 19: 49ers vs. Atlanta Falcons (5:20pm, NBC) [SNF]
Week 8, Oct. 26: 49ers at Houston Texans (10:00am, FOX)
Week 9, Nov. 2: 49ers at New York Giants (10:00am, CBS)
Week 10, Nov. 9: 49ers vs. Los Angeles Rams (1:25pm, FOX)
Week 11, Nov. 16: 49ers at Arizona Cardinals (1:05pm, FOX)
Week 12, Nov. 24: 49ers vs. Carolina Panthers (5:15pm, ESPN) [MNF]
Week 13, Nov. 30: 49ers at Cleveland Browns (10:00am, CBS)
Week 14, Dec. 7: BYE WEEK
Week 15, Dec. 14: 49ers vs. Tennessee Titans (1:25pm, FOX)
Week 16, Dec. 22: 49ers at Indianapolis Colts (5:15pm, ESPN) [MNF]
Week 17, Dec. 28: 49ers vs. Chicago Bears (5:20pm, NBC) [SNF]
Week 18, Jan. 3/4: 49ers vs. Seattle Seahawks (TBD)
Cardinals-49ers games
The Cardinals face the 49ers in Santa Clara in Week 3. The 49ers will have been on the road against the Saints, the Cardinals’ Week 1 opponent. Then they will stay at home to play the Jaguars.
Meanwhile, the Cardinals will have just played the Carolina Panthers at home and will have a Thursday night game staring them in the face four days later.
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Later in the season, the Niners face the Cardinals at State Farm Stadium in Week 11. They will have had a normal week of rest having played the Rams at home the previous week, and they will return home to face the Panthers the next week.
The Cardinals will have been on the road against the Seahawks in Week 10 and will stay home to face Jacksonville the next week.
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This article originally appeared on Cards Wire: 49ers schedule: A look at their opponents before, after Cardinals
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