Five NFL games we can’t wait to watch in the 2025 season
The NFL schedule for the 2025-2026 season has been released. Here are a few games on our must-watch list.
The San Francisco 49ers are looking to bounce back from a year most fans would prefer to forget.
The usually unstoppable offense of Brock Purdy, Christian McCaffrey, Deebo Samuel Sr., George Kittle, McQueen High School alum Brandon Aiyuk and more were broken down by injuries in 2024.
Now Samuel is a Washington Commander, Aiyuk is recovering from injury and 49ers fans are left wondering if their Super Bowl window is closing.
The 49ers are still co-favorites to win the NFC West, and betting against Kyle Shanahan has been a losing effort for the majority of his NFL career.
See below for the full 49ers schedule and how to get tickets to support your 49ers in person.
Tickets to each San Francisco 49ers game, both home and away, are already available for purchase. Some key home matchups for the 49ers include divisional games against the Seattle Seahawks, Arizona Cardinals and Los Angeles Rams and a first look at the two top picks in the 2025 NFL Draft, Cam Ward with the Tennessee Titans and Travis Hunter with the Jacksonville Jaguars.
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San Francisco 49ers 2025 NFL schedule
Week 1: San Francisco 49ers vs. Seattle Seahawks – 1:05 p.m. PT at Lumen Field in Seattle, Washington. – Shop ticketsWeek 2: San Francisco 49ers vs. New Orleans Saints – 10 a.m. PT at Caesars Superdome in New Orleans, Louisiana – Shop ticketsWeek 3: Arizona Cardinals vs. San Francisco 49ers – 1:25 p.m. PT at Levi’s Stadium in Santa Clara, California. – Shop ticketsWeek 4: Jacksonville Jaguars vs. San Francisco 49ers – 1:05 p.m. PT at Levi’s Stadium in Santa Clara, California. – Shop ticketsWeek 5: San Francisco 49ers vs. Los Angeles Rams – 5:15 p.m. PT at SoFi Stadium in Inglewood, California. (Thursday Night Football) – Shop ticketsWeek 6: San Francisco 49ers vs. Tampa Bay Buccaneers – 10 a.m. PT at Raymond James Stadium in Tampa, Florida. – Shop ticketsWeek 7: Atlanta Falcons vs. San Francisco 49ers – 5:20 p.m. PT at Levi’s Stadium in Santa Clara, California. (Sunday Night Football) – Shop ticketsWeek 8: San Francisco 49ers vs. Houston Texans – 10 a.m. PT at NRG Stadium in Houston, Texas. – Shop ticketsWeek 9: San Francisco 49ers vs. New York Giants – 10 a.m. PT at MetLife Stadium in East Rutherford, New Jersey. – Shop ticketsWeek 10: Los Angeles Rams vs. San Francisco 49ers – 1:25 p.m. PT at Levi’s Stadium in Santa Clara, California. – Shop ticketsWeek 11: San Francisco 49ers vs. Arizona Cardinals – 1:05 p.m. PT at State Farm Stadium in Glendale, Arizona. – Shop ticketsWeek 12: Carolina Panthers vs. San Francisco 49ers – 5:15 p.m. PT at Levi’s Stadium in Santa Clara, California. (Monday Night Football) – Shop ticketsWeek 13: San Francisco 49ers vs. Cleveland Browns – 10 a.m. PT at Huntington Bank Field in Cleveland, Ohio. – Shop ticketsWeek 14: BYE WEEKWeek 15: Tennessee Titans vs. San Francisco 49ers – 1:25 p.m. PT at Levi’s Stadium in Santa Clara, California. – Shop ticketsWeek 16: San Francisco 49ers vs. Indianapolis Colts – 5:15 p.m. PT at Lucas Oil Stadium in Indianapolis, Indiana. (Monday Night Football) – Shop ticketsWeek 17: Chicago Bears vs. San Francisco 49ers – 5:20 p.m. PT at Levi’s Stadium in Santa Clara, California. (Sunday Night Football) – Shop ticketsWeek 18: Seattle Seahawks vs. San Francisco 49ers – TBD at Levi’s Stadium in Santa Clara, California. – Shop tickets
San Francisco 49ers NFL Week 1 opponent
The 49ers start the 2025 regular season against the Seattle Seahawks.
When does the 2025 NFL season start?
The 2025 NFL regular season kicks off in Philadelphia when the defending champion Eagles host the Dallas Cowboys. The 49ers season will begin on Sunday, Sept. 7, against the Seattle Seahawks.
How to watch the NFL, TV channels, streaming services
The regular season begins on Thursday, Sept. 4, when the Eagles host the Cowboys. There are a number of ways to watch the NFL this season, as games are played on a variety of TV channels and streaming services. Make sure to subscribe in order to catch every second of heart-pounding NFL action this season.
NBC – Sunday Night Football will once again be telecast on NBC, as will the opening game of the NFL season between the Philadelphia Eagles and Dallas Cowboys. You can stream these games with a Fubo FREE trial or with Peacock.FOX – Many NFL games will be broadcast on FOX, either nationally or in local markets. FOX is available to stream with a Fubo FREE trial, or on Sling.CBS – Many NFL games, mainly AFC teams, will be broadcast on CBS, either nationally or in local markets. CBS is available to live stream with a Fubo FREE trial, or with Paramount+.Prime Video – Amazon is back as the exclusive hosts of Thursday Night Football in 2025. Beginning in Week 2, watch Thursday Night Football only on Prime Video, and don’t forget about the Black Friday game between the Philadelphia Eagles and Chicago Bears or the Christmas Day game between the Chiefs and Broncos.Peacock – In addition to being a streaming option for Sunday Night Football, Peacock will also carry an exclusive Week 17 NFL game near the end of the regular season.Paramount+ – The full CBS NFL schedule carries more than 100 games this season, all of which are available to watch on Paramount+ in your local market.YouTube – One of the NFL’s international games will again be played in Brazil this year as the Kansas City Chiefs take on the Los Angeles Chargers on Friday, Sept. 5. The game is exclusively available for streaming on YouTube.Netflix – The streaming giant will exclusively have two Christmas Day games again in 2025, and both appear to be divisional battles that could decide the fate of the NFC North and NFC East.
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