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The Arizona Cardinals and San Francisco 49ers play on Sunday, Oct. 6, at Levi’s Stadium in a game on the NFL Week 5 schedule.
Which team will win the NFL Week 5 game?
Check out these NFL Week 5 picks and NFL Week 5 predictions for the game, which can be seen at 1:05 p.m. MST on FOX (stream with free trial from FUBO).
The 49ers are a 7.5-point favorite over the Cardinals in NFL Week 5 odds for the game, courtesy of BetMGM Sportsbook.
San Francisco is -375 on the moneyline, while Arizona is +300.
The over/under (point total) is set at 49.5 points.
NFL Week 5 picks: Buccaneers vs Falcons | Jets vs Vikings | Panthers vs Bears | Ravens vs Bengals | Bills vs Texans | Colts vs Jaguars | Dolphins vs Patriots | Browns vs Commanders | Raiders vs Broncos | Cardinals vs 49ers | Packers vs Rams | Giants vs Seahawks | Cowboys vs Steelers | Saints vs Chiefs | The Arizona Republic’s predictions
Watch Cardinals at 49ers live with FUBO (free trial)
Jeremy Cluff writes: “The 49ers are the biggest favorite of the week. Can the Cardinals shock San Francisco? Can they even keep this game close? Not the way they are playing.”
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Bookies.com: Bet the Cardinals with the points vs 49ers
Bill Speros writes: “The 49ers active roster remains in flux. But their defense will be enough to win this one at home. But a full TD cover might be too much to ask, especially given how the Cardinals can score big-yardage-play TDs with Kyler Murray and Marvin Harrison Jr. Especially in garbage time.”
NFL Week 5 odds: Point spreads, moneylines, over/unders for betting on NFL games this week
The site’s formula predicts that the Cardinals will win the NFL Week 5 game against the 49ers.
NFL Week 5 schedule: Television channels, how to watch, stream games
ESPN: 49ers have a 70.5% chance to beat Cardinals on Sunday
The site gives the Cardinals a 29.2% shot at winning the NFL Week 5 game, with the remaining percentage accounting for a tie.
NFL Week 5 announcers: Television broadcasters, announcing crews for Week 5 NFL schedule
Dimers: 49ers 26, Cardinals 19
It writes: “After extensive simulations, our model gives the Cardinals a win probability of 23%, while the 49ers have a win probability of 77%.”
NFL Week 5 predictions: ESPN matchup predictor’s picks, win probabilities for this week
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Reach Jeremy Cluff at [email protected]. Follow him on X, formerly Twitter @Jeremy_Cluff.
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