The San Francisco 49ers (2-2) will play NFC West rivals, the Arizona Cardinals (1-3), on Sunday, October 6, 2024 at Levi’s Stadium. The 49ers are notable favorites in this one, with the spread posted at 7.5 points. The over/under for the outing is 49 points.
Facing the New England Patriots in their last contest, the 49ers won 30-13.
Against the Patriots, Brock Purdy completed 15 of 27 passes for 288 yards, with one touchdown and one interception, for the Niners.
The Cardinals lost against the Washington Commanders in their last game, 42-14.
49ers vs Cardinals betting information
NFL odds courtesy of BetMGM Sportsbook. Odds updated Sunday at 4:53 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread Favorite: San Francisco (-7.5)
Moneyline: San Francisco (-355), Arizona (+278)
Total: 49 points
49ers betting insights
San Francisco was 5-3 overall, and 3-5 against the spread, at home last year.
The 49ers have covered the spread in a matchup two times this season (2-2-0).
At home last season, San Francisco had two wins ATS (2-2) as 7.5-point favorites or greater.
In games they have played as 7.5-point favorites or more, the 49ers have a perfect ATS record of 1-0.
In eight games at home last season, San Francisco went over the total five times.
Games involving the 49ers have hit the over three times this season.
49ers leaders
Purdy: 1,130 PASS YDS / 282.5 YPG / 68.9% / 5 TD / 2 INT / 18 CAR / 75 RUSH YDS / 0 TD
Jordan Mason: 91 CAR / 447 YDS / 111.8 YPG / 3 TD / 6 REC / 57 YDS / 14.3 YPG / 0 TD
Jauan Jennings: 21 REC / 364 YDS / 91 YPG / 3 TD
Deebo Samuel: 16 REC / 222 YDS / 74 YPG / 0 TD
Brandon Aiyuk: 13 REC / 167 YDS / 41.8 YPG / 0 TD
49ers vs Cardinals game info
Date: Sunday, October 6, 2024
Time: 4:05 p.m. ET
City: Santa Clara, California
Venue: Levi’s Stadium
TV Channel: FOX
Live Stream: Fubo (Watch 49ers vs Cardinals on Fubo)
Watch the San Francisco 49ers all season on Fubo!
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