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The San Francisco 49ers and Seattle Seahawks play Thursday, Oct. 10, at Lumen Field in the first game on the NFL Week 6 schedule.
Which team will win the Thursday Night Football game?
Check out these NFL Week 6 picks and NFL Week 6 predictions for the game, which can be seen at 5:15 p.m. MST on Prime Video (stream on Amazon).
The 49ers are a 3-point favorite over the Seahawks in NFL Week 6 odds for the game, courtesy of BetMGM Sportsbook.
San Francisco is -160 on the moneyline, while Seattle is +135.
The over/under (point total) is set at 47.5 points.
NFL Week 6 picks: 49ers vs Seahawks | Jaguars vs Bears | Commanders vs Ravens | Cardinals vs Packers | Texans vs Patriots | Buccaneers vs Saints | Browns vs Eagles | Colts vs Titans | Chargers vs Broncos | Steelers vs Raiders | Falcons vs Panthers | Lions vs Cowboys | Bengals vs Giants | Bills vs Jets | The Arizona Republic’s predictions
Watch 49ers at Seahawks live with Amazon Prime
Jeremy Cluff writes: “What’s going on with the 49ers? Their problems seem to extend far beyond just being without Christian McCaffrey. Still, San Francisco would tie for the NFC West division lead with a win in this game.”
NFL power rankings Week 6: Where are 49ers, Seahawks now?
Bookies.com: Bet the under in 49ers vs Seahawks game
Bill Speros writes: “Both teams limp into this short-week NFC West showdown. Upsets were on the menu for the Seahawks, who somehow lost to the Giants despite running back a fumble 102 yards. And the Niners, who blew a 10-point lead in the 4th quarter in a 24-23 loss to the Cardinals. The 49ers have won 3 straight against Seattle. Both defenses will keep this one close. And low scoring.”
NFL Week 6 odds: Point spreads, moneylines, over/unders for betting on games this week
The site’s formula predicts that the 49ers will win the NFL Week 6 game against the Seahawks.
NFL Week 6 schedule: Television channels, how to watch, stream games this week
ESPN: 49ers have a 62% chance to beat Seahawks on Thursday Night Football
The site gives the Seahawks a 37.6% shot at winning the NFL Week 6 game, with the remaining percentage accounting for a tie.
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Dimers: 49ers 25, Seahawks 21
It writes: “After extensive simulations, our model gives the 49ers a win probability of 66%, while the Seahawks have a win probability of 34%.”
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Reach Jeremy Cluff at [email protected]. Follow him on X, formerly Twitter @Jeremy_Cluff.
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