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The San Francisco 49ers and Green Bay Packers play on Sunday, Nov. 24 at Lambeau Field in a game on the NFL Week 12 schedule.
Which team will win the NFL Week 12 game?
Check out these NFL Week 12 picks and NFL Week 12 predictions for the game, which can be seen at 2:25 p.m. MST on FOX (stream with free trial from FUBO).
The Packers are a 1.5-point favorite over the 49ers in NFL Week 12 odds for the game, courtesy of BetMGM Sportsbook.
Green Bay is -120 on the moneyline, while San Francisco is +100.
The over/under (point total) is set at 48 points.
NFL Week 12 picks: Steelers vs Browns | Chiefs vs Panthers | Vikings vs Bears | Titans vs Texans | Lions vs Colts | Patriots vs Dolphins | Buccaneers vs Giants | Cowboys vs Commanders | Broncos vs Raiders | 49ers vs Packers | Cardinals vs Seahawks | Eagles vs Rams | Ravens vs Chargers | Arizona Republic’s predictions
Watch 49ers at Packers live with FUBO (free trial)
Jeremy Cluff writes: “This game is pretty much a must-win for the 49ers, who are now 5-5 on the season. They’ll escape Green Bay with a very narrow victory.”
Sportsnaut: Packers 27, 49ers 24
Matt Johnson writes: “The Nick Bosa injury (oblique) looms large over this matchup. If the All-Pro edge rusher is unable to go, it’s hard to see this San Francisco 49ers pass rush consistently generating pressure on Jordan Love. From a clean pocket, Love is one of the best quarterbacks in football and the Green Bay Packers have the depth at wide receiver to find holes in the 49ers’ secondary. If Bosa plays, this is a 27-24 win for San Francisco over Green Bay.”
NFL Week 12 odds: Point spreads, moneylines, over/unders | Super Bowl odds | NFL MVP odds | NFL Coach of the Year odds | NFC West odds | NFC East odds | NFC North odds | NFC South odds | AFC West odds | AFC East odds | AFC North odds | AFC South odds
The site’s formula predicts that the Packers will win the NFL Week 12 game against the 49ers.
ESPN: Packers have a 53.5% chance to beat 49ers on Sunday
The site gives the 49ers a 46.1% shot at winning the NFL Week 12 game, with the remaining percentage accounting for a tie.
Dimers: 49ers 24, Packers 23
It writes: “After extensive simulations, our model gives the 49ers a win probability of 56%, while the Packers have a win probability of 44%.”
NFL strength of schedule: NFC rankings | AFC rankings
Bookies.com: Bert the Packers on the moneyline vs 49ers
Bill Speros writes: “The 49ers barely escaped from Tampa Bay with a 23-20 win in Week 10. The bottom fell out in a 20-17 loss at home to the Seahawks. At 5-5, the 49ers are on the outside looking in both the NFC West and NFC playoff picture. They legit need a win here to keep their playoff hopes in focus, given the likelihood of a tie-breaker coming into place to determine postseason entry or placement. They also sit underwater at 4-6 ATS. The same story holds in Green Bay. The Packers are 3rd in the NFC Central. They’ve won 5 of 7 games after (barely) beating Chicago. The Packers are 7-3 SU but just 4-6 ATS. The 49ers have failed to cover 7 of 8 games against teams with a winning record. Tom Brady will be guiding you in the booth here. But will Jordan Love or Brock Purdy do their best Brady imitation in a nationally televised game with playoff implications? Love is in the air.”
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Reach Jeremy Cluff at [email protected]. Follow him on X, formerly Twitter @Jeremy_Cluff.
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